Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams
Identifieur interne : 000783 ( France/Analysis ); précédent : 000782; suivant : 000784Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams
Auteurs : Nathalie Hinfray [France] ; Olivier Palluel [France] ; Benjamin Piccini [France] ; Wilfried Sanchez [France] ; Selim Ait-Aissa [France] ; Patrice Noury [France] ; Elena Gomez [France] ; Perrine Geroudie [France] ; Christophe Minier [France] ; François Brion [France] ; Jean-Marc Porcher [France]Source :
- Science of the Total Environment [ 0048-9697 ] ; 2010.
Abstract
The aim of this study was to assess endocrine disruptive effects in wild population of fish in five French rivers selected to represent different pollution contexts at two seasons (summer and fall). For that purpose, a panel of biometrical parameters (length, weight, and gonado-somatic index: GSI) and biochemical (ethoxyresorufin-O-deethylase: EROD, vitellogenin: VTG, and brain aromatase) and histological biomarkers (gonads histology) were used in chub (Leuciscus cephalus), a common cyprinid fish species. In fish from the reference site, EROD activity and VTG levels were low at the two seasons. Brain aromatase activities (AAs) were similar to other species and increased with increasing GSI and gonad maturation. Among the four contaminated sites, the Jalle d'Eysines River was the most impacted site. At this site, fish were exposed to estrogenic substances as demonstrated by the VTG induction in males and the arrest of development of the gonads that led to lower brain AA compared to fish from the reference site. In fish from other contaminated sites, EROD activity was induced as compared to fish from the reference site and some males had elevated concentrations of VTG. Moreover, the presence of aromatase-inhibiting compounds was demonstrated in the sediments of three contaminated sites, even if the precise nature of contaminants is not known. This study provides new data concerning endocrine disruption in wild fish populations inhabiting French rivers and demonstrates that measurements of in vivo and in vitro aromatase could be used as biomarkers of endocrine disruption in field studies.
Url:
DOI: 10.1016/j.scitotenv.2010.01.003
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000112
- to stream Hal, to step Curation: 000112
- to stream Hal, to step Checkpoint: 000473
- to stream Main, to step Merge: 000936
- to stream Main, to step Curation: 000934
- to stream Main, to step Exploration: 000934
- to stream France, to step Extraction: 000783
Links to Exploration step
Hal:ineris-00961748Le document en format XML
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status="VALID"><orgName>Institut National de l'Environnement Industriel et des Risques</orgName><orgName type="acronym">INERIS</orgName><desc><address><country key="FR"></country></address><ref type="url">http://www.ineris.fr/</ref></desc><listRelation><relation active="#struct-300023" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300023" type="direct"><org type="institution" xml:id="struct-300023" status="VALID"><orgName>INERIS</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Porcher, Jean Marc" sort="Porcher, Jean Marc" uniqKey="Porcher J" first="Jean-Marc" last="Porcher">Jean-Marc Porcher</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3186" status="VALID"><orgName>Institut National de l'Environnement Industriel et des Risques</orgName><orgName type="acronym">INERIS</orgName><desc><address><country key="FR"></country></address><ref type="url">http://www.ineris.fr/</ref></desc><listRelation><relation active="#struct-300023" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300023" type="direct"><org type="institution" xml:id="struct-300023" status="VALID"><orgName>INERIS</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author></analytic><idno type="DOI">10.1016/j.scitotenv.2010.01.003</idno><series><title level="j">Science of the Total Environment</title><idno type="ISSN">0048-9697</idno><imprint><date type="datePub">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="mix" xml:lang="it"><term>AROMATASE</term><term>CHUB</term><term>ENDOCRINE DISRUPTION</term><term>HISTOLOGY</term><term>VITELLOGENIN</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this study was to assess endocrine disruptive effects in wild population of fish in five French rivers selected to represent different pollution contexts at two seasons (summer and fall). For that purpose, a panel of biometrical parameters (length, weight, and gonado-somatic index: GSI) and biochemical (ethoxyresorufin-O-deethylase: EROD, vitellogenin: VTG, and brain aromatase) and histological biomarkers (gonads histology) were used in chub (Leuciscus cephalus), a common cyprinid fish species. In fish from the reference site, EROD activity and VTG levels were low at the two seasons. Brain aromatase activities (AAs) were similar to other species and increased with increasing GSI and gonad maturation. Among the four contaminated sites, the Jalle d'Eysines River was the most impacted site. At this site, fish were exposed to estrogenic substances as demonstrated by the VTG induction in males and the arrest of development of the gonads that led to lower brain AA compared to fish from the reference site. In fish from other contaminated sites, EROD activity was induced as compared to fish from the reference site and some males had elevated concentrations of VTG. Moreover, the presence of aromatase-inhibiting compounds was demonstrated in the sediments of three contaminated sites, even if the precise nature of contaminants is not known. This study provides new data concerning endocrine disruption in wild fish populations inhabiting French rivers and demonstrates that measurements of in vivo and in vitro aromatase could be used as biomarkers of endocrine disruption in field studies.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Haute-Normandie</li><li>Région Normandie</li></region><settlement><li>Le Havre</li></settlement><orgName><li>Université du Havre</li></orgName></list><tree><country name="France"><noRegion><name sortKey="Hinfray, Nathalie" sort="Hinfray, Nathalie" uniqKey="Hinfray N" first="Nathalie" last="Hinfray">Nathalie Hinfray</name></noRegion><name sortKey="Ait Aissa, Selim" sort="Ait Aissa, Selim" uniqKey="Ait Aissa S" first="Selim" last="Ait-Aissa">Selim Ait-Aissa</name><name sortKey="Brion, Francois" sort="Brion, Francois" uniqKey="Brion F" first="François" last="Brion">François Brion</name><name sortKey="Geroudie, Perrine" sort="Geroudie, Perrine" uniqKey="Geroudie P" first="Perrine" last="Geroudie">Perrine Geroudie</name><name sortKey="Gomez, Elena" sort="Gomez, Elena" uniqKey="Gomez E" first="Elena" last="Gomez">Elena Gomez</name><name sortKey="Minier, Christophe" sort="Minier, Christophe" uniqKey="Minier C" first="Christophe" last="Minier">Christophe Minier</name><name sortKey="Noury, Patrice" sort="Noury, Patrice" uniqKey="Noury P" first="Patrice" last="Noury">Patrice Noury</name><name sortKey="Palluel, Olivier" sort="Palluel, Olivier" uniqKey="Palluel O" first="Olivier" last="Palluel">Olivier Palluel</name><name sortKey="Piccini, Benjamin" sort="Piccini, Benjamin" uniqKey="Piccini B" first="Benjamin" last="Piccini">Benjamin Piccini</name><name sortKey="Porcher, Jean Marc" sort="Porcher, Jean Marc" uniqKey="Porcher J" first="Jean-Marc" last="Porcher">Jean-Marc Porcher</name><name sortKey="Sanchez, Wilfried" sort="Sanchez, Wilfried" uniqKey="Sanchez W" first="Wilfried" last="Sanchez">Wilfried Sanchez</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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